The purpose of this study is to explore the impact of human resource management on knowledge creation. To this end, hypotheses were developed to explain the relationship between commitment-based human resource management and knowledge creation, focusing on the mediating effects of peer trust and organizational trust. Data were collected from the research and development divisions of technology-intensive firms, where innovation through knowledge creation constitutes a critically important part of business activities. The results showed that commitment-based human resource management systems have a positive (+) relationship with both peer trust and organizational trust, and that peer trust and organizational trust fully mediate the relationship between commitment-based human resource management systems and knowledge creation, thereby supporting all hypotheses of this study. The significance of this study lies in its focus on human resource management as an antecedent of knowledge creation, and in theorizing and empirically testing the relational mechanism between human resource management systems and knowledge creation through the mediating variable of trust.